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Q:

Define “opportunity cost” and “social cost”. Explain how each of them would affect government decision to develop a new oil field in Kribi. (20marks)

Remark:

The first part of the question is to do with basic concepts from the text book or exercise book. In actual fact, these concepts should be explained and not defined. Examples should be given and very good ones. The second part of the question is to do with cost and benefit analysis in decision making by the government.

A:

Opportunity Cost and Social Cost: Explanation and Impact on Government Decision to Develop a New Oil Field in Kribi


1. Opportunity Cost

Definition and Explanation:
Opportunity cost refers to the value of the next best alternative that is foregone when a decision is made. It is not just about monetary costs but also includes the benefits that could have been obtained from the alternative use of resources. For example, if the government allocates land and capital to develop an oil field in Kribi, the opportunity cost might be the benefits from investing that same land and capital into agriculture or tourism instead.

Example:
Suppose the government chooses to develop the oil field. The opportunity cost could be the potential income from tourism if the land were preserved as a national park, or the benefits from expanding agriculture in the region.


2. Social Cost

Definition and Explanation:
Social cost encompasses all the costs to society resulting from an economic activity, including both private costs (borne directly by the producer or consumer) and external costs (costs imposed on third parties or the environment). Externalities such as environmental pollution, health hazards, and loss of biodiversity are key components of social costs.

Example:
Developing the oil field might generate economic benefits such as revenue and employment, but it could also lead to environmental degradation, air and water pollution, and health problems among local communities. These negative effects are social costs because they impact society beyond the direct stakeholders involved in the oil extraction.


3. Impact on Government Decision-Making for Developing the Oil Field in Kribi

a. Considering Opportunity Cost:

  • The government must evaluate whether developing the oil field maximizes national benefits. If resources (land, capital, labor) could generate higher returns elsewhere, such as in agriculture or renewable energy, then the opportunity cost of pursuing oil development is high.
  • For example, if tourism in Kribi, with its beaches and natural scenery, could generate more sustainable revenue than oil extraction, the government might decide against developing the oil field to avoid foregone tourism benefits.

b. Considering Social Cost:

  • The government should also account for externalities associated with oil development. If environmental degradation leads to long-term health costs, loss of biodiversity, or climate change impacts, these social costs could outweigh short-term economic gains.
  • For instance, if oil spills or pollution threaten fisheries or local livelihoods, the social costs could be substantial, prompting the government to implement strict regulations or consider alternative development options.

c. Cost-Benefit Analysis:

  • The decision involves weighing the economic benefits (such as increased revenue, employment, and energy security) against the opportunity costs and social costs.
  • If the social costs are high and the opportunity costs indicate better alternative uses of resources, the government might opt to delay or forego oil development, or implement measures to mitigate environmental damage.

opportunity cost helps the government recognize what they forgo when choosing oil development over other possibilities like tourism or agriculture. Social cost ensures they consider wider societal impacts, especially environmental and health-related externalities. A thorough cost-benefit analysis incorporating these costs would lead to more sustainable and informed decisions regarding the development of the Kribi oil field.

Year: June 2006 | Subject: Economics | Topic: BASIC CONCEPTS ECONOMIC SYSTEMS AND RESOURCE ALLOCATION

    Q:

    (a)      What is meant by a production possibility frontier? (10 marks).

    (b)     Which basic economic principles does ties concept explain? (10 marks)

    Remark:

    A rather direct question but care must be taken to explain the basic economic principles with respect to a production possibility curve.

    A:

    Economic theory is usually developed to help explain economic happenings around us and so we get to talk of the concept of a production possibility frontier (PPF). A PPF shows the maximum combinations of two goods or services that an economy or on economic entity can produce at a given time with its available resources and technology. It is possible to have a PPF with increasing costs, decreasing costs or constant costs. This essay focuses on the most realistic option of a PPF which is that with increasing costs.

    In order to derive a PPC with increasing costs, the following assumptions are made:

    That an economy can produce only two goods- capital goods and consumer goods ;

    That there is a fixed quantity and quality of resources our given period of time;

    That there are increasing costs of production or that there are diminishing returns to production or that resources are not perfectly adaptable between different uses.

    That technology is fixed.

    On the basis of these assumptions, it is possible to envisage the following production possibility schedule and the resultant production possibilities curve.

    Production possibilities.

    Product combination

    Capital goods

    Consumer goods

    A

    70

    0

    B

    50

    30

    C

    30

    40

    D

    0

    50

     

    Production possibilities curve

    20 40 60 Consumer goods

     

    Points A, B, C and D are points on the PPC while points E is within the PPC. Point F is out of the PPC. Point E can produced when resource are not fully or efficiently used while profit F cannot be produced at present.

    A PPG can enable us explain the basic economic concepts of scarcity, choice and opportunity cost.

    Scarcity means limited in supply. At a given time and with the resources and technology available, it is not possible to produce output combination F because of scarcity of economic resources as we see this product combination is out of the PPG.

    Given that an economy cannot provide all of what it wants, it is bound to make choices. Making a choice means making a decision to take one thing out of some given possibilities. The economy can for instance chose to produce 70 capital goods and zero consumer goods or 50 capital goods and 30 consumer goods etc.

    In the process of making a choice, there are opportunity costs. An opportunity cost is the cost of something in terms of the next best forgone alternative. For instance, to move from product combination B to product combination C entails an opportunity cost. Twenty 20 units of capital goods would have to be given up in order to produce 10 additional units of consumer goods. Twenty capital goods are thus the opportunity cost of 40 capital goods.

    It is this seen that a PPG can be used to explain the basic economic concepts of scarcity, choice and opportunity cost and may equally be used to explain other concepts like economic growth etc.

    Year: June 2013 | Subject: Economics | Topic: BASIC CONCEPTS ECONOMIC SYSTEMS AND RESOURCE ALLOCATION

      Q:

      Why may it be impossible for a country to increase the production of both capital goods and consumer goods at the same time when it is already on its production possibility frontier?  (20marks)

      Remark:

      A production possibility curve or preferably a production possibilities curve shows the maximum combinations of goods or services that an economy or an economic entity can produce with its given level of technology. It logically follows that once on that curve, it becomes impossible to increase the production of both capital goods and consumer goods at the same time as the following write up illustrates.

      A:

      A production possibilities frontier or curve (PPC) shows the possible combinations of goods that an economy or an economic entity like a firm or a plant can produce when all its resources are fully and efficiently utilized with its given level of technology. This concept is of prime importance in illustrating the basic economic

      concepts of scarcity, choice, opportunity cost as well as the notion of economic growth .A careful explanation of the notion of a PPC with the relevant assumptions would enable us see why it is impossible for a country to increase the production of both capital goods and consumer goods once on its PPC as well as throwing lighten other related issues.

      Consider a given country, say Lilyputia for which we proceed to develop its PPC. We further assume that:

      The quantity and quality of economic resources available for use in Lilyputia during the year are fixed.

      Two broad categories of goods are to be produced i.e capital goods and consumer goods.

      Some resources are better adapted to the production of capital goods than to the production of consumer goods. (If we assume all resources are equally efficient or adapted in the production of both goods, then we would have a straight line PPC and not a concave shaped PCC as in this case).

      Technology is fixed and does not advance during the year.

      On the basis of the aforementioned assumptions, we can come up with the following production combinations for capital goods and consumer goods.

      Product combination

      Output of capital goods

      Output of consumer goods

      Combination 1 (A)

      50

      0

      Combination 2 (B)

      40

      300

      Combination 3 (C)

      20

      500

      Combination 4 (D)

      0

      550

       

      With the help of these production combinations, it is then possible to derive the following PPC by plotting the aforementioned product combinations as shown on

       

      We now assume that this economy of Lilyputia is currently producing 40 units of capital goods and 300 units of consumer goods i.e point B. If the economy now

      wants to increase the production of consumer goods to 500 units, it can only do so by reducing the production of capital goods to 20 units so as to produce 200 additional units of consumer goods. In other words, the opportunity cost in this case of producing 200 additional units of consumer goods is 20 units of capital goods. This is so for the simple reason that there is a limit to the amount of consumer goods and capital goods that can be produced at any given time period with available technology and resources etc. This means that more of a good can only be produced by reducing the potential output of the other good. In short, given the assumptions of a PPC as earlier outlined, it is impossible for Lilyputia or for any other country to increase the production of both capital goods and consumer goods at the same time when the country is already on its PPC.

      We can further elucidate on the aforementioned point by assuming that Lilyputia is producing at point X which is NOT a point on its PPC but a point INSIDE its PPC. It then becomes possible to increase the production of both capital goods and consumer goods by moving to ANY point on its PPC and by either FULLY and EFFICIENTLY using its resources.

      If again we consider another point like point Y which is NOT on Lilyputia’s PPC, it may be possible to produce more of capital goods and consumer goods if and only if there is an outward shift of the PCC. We then talk of economic growth which may have been brought about by say the discovery of additional resources, improved technology, etc.

      By way of conclusion, we Can say that given the assumptions of a PPC, it is impossible to produce more of capital goods and consumer goods once on a PPC. If this were to be possible, then it would be a violation of the very concept of a PPC which concept illustrates:

      (i)            Scarce resources i.e there is a limit to the amount of what we can produce at a given time with available resources and technology thus obliging us to make a choice;

      (ii)            Opportunity costs i.e more of a given good can only be obtained by reducing the potential production of another goods.

      Year: June 2000 | Subject: Economics | Topic: BASIC CONCEPTS ECONOMIC SYSTEMS AND RESOURCE ALLOCATION

        Q:

        “Even though Economics and Meteorology are both sciences, the meteorologist is more exact in predicting weather changes than the economist is at predicting what will happen to an economy:” Explain.  (20marks)

        Remark:

        This question requires an explanation as to why scientific analyses are more exact in Meteorology than in Economics. A detailed knowledge of meteorology is not required because any other applied physical science like Biology or Physics could have been used in the place of Meteorology.

        A:

        Economics is a social science which seeks to study how individuals, firms and governments use scarce resources that have alternative uses to produce various goods and services and how these goods and services are distributed for present and future consumption. On the other hand, Meteorology is simply the scientific study of weather. All of the aforementioned subjects are sciences though the former is a social science while the latter may be termed a physical science. Although all of them are sciences, the meteorologist is more exact in predicting weather changes than the economist is at predicting what will happen to an economy as we would seek to explain in the essay that follows.

        A discipline is said to be a science if it uses the scientific method of analysis. The scientific method evolves on concepts such as objectivity of approach i.e the attempt to observe things as they are without

        falsifying observations to accord with some preconceived view.

        Scientific method also involves the interplay of inductive reasoning (reasoning from specific observations and experiments to more general hypotheses and theories) and deductive reasoning (reasoning from hypothesis to account for specific experimental results). By such reasoning processes, science attempts to develop broad laws e.g that rain is precipitated by a decrease in temperature, not by a change in atmospheric pressure or that more of a good would be bought at lower prices everything being equal. These scientific discoveries then become part of our understanding of the world. Meteorology and Economics are both sciences to the extent that they both use the scientific method just described.

        Although Meteorology and Economics are both sciences, Meteorology is a physical science i.e a science that deals with physical processes like rainfall, wind etc while Economics is a social science that deals with the complex behaviour of human beings. It follows that scientific analysis and predictions are more difficult in Economics than in Meteorology for the following reasons.

        The most obvious limitation of the economist and of the social scientist in general is that he/she cannot carry out a laboratory experiment to test his/her hypothesis. The social scientist cannot put a group of human beings into a controlled situation to study anything about them whereas the meteorologist can easily set up a rain gauge somewhere so as to experiment and come out with more or less accurate findings. It then becomes easy to understand why the meteorologist can easily make accurate predictions with respect to rainfall as opposed to the economist’s predictions about investments.

        It is equally seen that the laboratory of the social scientist which is human society is further complicated by the fact that human behaviour is far from being identical. If there is an increase in the price of a good or in the rate of interest, all human beings would not react in exactly the same way.

        Human beings are indeed very complex and their varying behaviour may stem from the fact that they belong to different schools of thought, may have different sets of values etc.

        If atoms are however placed under identical situations and are subject to say heat or pressure, they would always react in the same way. It follows that the meteorologist is more likely to make accurate predictions in his field compared to the economist.

        The economist is concerned with human behaviour in a very complex world where many things are changing simultaneously. For instance, the price of a good can rise by 20% and there is a 30% rise in real incomes and so the economist would likely be wrong if she predicts a fall in quantity demanded following the increase in price.

         

        The meteorologist just like any other natural scientist can easily “hold other things constant” while studying the effects which changes on X may have on Y. It follows that the predictions of the meteorologist would likely be more accurate compared to those of the poor economist. Given that the economist cannot hold other things constant, the most he/she can do is to assume that other things remain constant and this explains why propositions in economics often begin with the phrase “if other things remain equal” (ceteris paribus).

        Although the meteorologist is generally more accurate in predicting weather changes than the economist is at predicting what will happen to the economy, it does not follow that the predictions of the economist are that unreliable. The fact that all people are different is not so much of a handicap to the economist or to the social scientist as it may appear at first sight. While the behaviour of any one person may be unpredictable, this is not necessarily true of the whole group. It follows that the economist is capable of making generalizations about economic groups (workers, investors, producers, importers etc) which are quite dependable guides on their expected behaviour. Econometrics may in the near future render predictions in Economics a little bit more reliable although the accuracy gap between the two sciences is likely to remain

        Year: June 1994 | Subject: Economics | Topic: BASIC CONCEPTS ECONOMIC SYSTEMS AND RESOURCE ALLOCATION

          Q:

          “If a price system did not exist as a means of allocating resources, it would be necessary to create one”. How far do you agree or disagree with this statement? 

          Remark:

          This question requires a discussion of the features and in particular the working of the price mechanism (market economy, price system, invisible hand) and to show that to a greater extent the price system is efficient although it could have a few weaknesses.

          A:

          The price mechanism in a market economy is what determines what, how and for whom to produce through the interaction of buyers and sellers. The price mechanism is essentially a process by which buyers express what they want to buy and sellers respond by indicating what they are willing to sell. Their combined activities result in the prevailing market price at which the good or service is exchanged.

          Consumers determine what will be produced through their spending decisions, or money votes, i.e. consumer sovereignty. Producers will then produce those goods desired, but since they are profit motivated, they will produce only those goods and services that are profitable. They will use the cheapest and most effective combinations of factors of production for maximum profit, and as such determine how the goods are produced. Those consumers, who can pay the price, get to enjoy these goods. In effect, for whom the good is produced is also decided by the market. In this way the price system acts, as it were, like a sophisticated computer, registering people’s preferences for different goods, transmitting these preferences to those responsible for producing the goods, and moving the factors to produce them. Thus the essential feature of the price mechanism or price system is the price signal.

          The price system seems to be the best mechanism for allocating resources in many ways.

          One advantage is that the price mechanism can run on its own. The fact that its workings are automatic means that there is no need for costly and cumbersome artificial coordination of economic decisions by the government or ruling body, and so massive bureaucratic costs are eliminated.

          The aforementioned feature also means that the economy can respond rapidly to changing demand and supply conditions.

          The market system is equally very efficient. The whole structure and organization of the market is the most conducive for generating wealth. People are able to work in careers of their own, and can invest in whatever businesses they want. This freedom and the pursuit of self-interest generates economic efficiency.

          There is an optimal allocation of resources in that there is economic efficiency. In a highly competitive market situation, there will be both allocative and productive efficiency. This means that the right amount of every commodity is produced and they are produced at the least cost.

          The market system is also argued to be the best allocator of resources for society because it allows for private ownership of wealth. This prevents the ruling body from having too much power and in so doing, safeguards the existence of personal liberty and choice. If private ownership of property were limited or controlled, then the ruling body would accumulate wealth and power at the expense of society.

          There are however many instances in which the price mechanism has failed to provide the best allocation of resources. When this happens, there is said to be market failure.

          One major disadvantage of the price system is that it fails to provide for the poor and the needy because the allocation of resources is based on a consumer’s purchasing power, not need. This results in the production of luxury goods for the rich at the expense of basic necessities of the starving poor. As a result of the inequality of income and wealth, the claims of consumer sovereignty and choice become questionable.

          The high level of competition that is necessary for efficient production of goods is also very often absent in the real world. Monopolies and Oligopolies often dominate in markets. They often charge high prices and earn abnormal profit at the expense of consumers.

          Advertising and aggressive marketing strategies also disrupt the effective functioning of the price system. This is because demand is distorted by persuading consumers to and even tricking them into buying what these firms are selling.

          Another weakness of the price system or market failure arises because of the failure of the price system to take into account both the explicit and the implicit costs of production. Only private costs and benefits are taken into consideration by the price system. It follows that there wouldn’t be a socially desirable level of production of goods without external costs and/or benefits taken into consideration. The practices of some firms may therefore be socially undesirable and bringing about pollution, under and over production etc.

          A free market economy will also result in the so called trade cycle, where there are periodical booms and

          slumps. This will result in alternating periods of unemployment and inflation. Such instability may discourage investment.

          We may end up evoking an ethical objection to the market economy. It is held that a free-market economy, by rewarding self-interested behaviour, may encourage selfishness, greed, materialism and the acquisition of power.

          By way of conclusion, it can still be said that the price system or the market economy is by far the most awesome wealth generating economic system mankind has ever known. This is true both in theory and through empirical evidence. The fall of the command economies of the world further strengthens the case for the market system. The price system however has its own weaknesses as earlier pointed out. The best way to allocate resources thus seems to be to have limited government intervention in what is basically a market economy using the price system.

          Year: June 1994 | Subject: Economics | Topic: BASIC CONCEPTS ECONOMIC SYSTEMS AND RESOURCE ALLOCATION

            Q:

            22.      (a) State five disadvantages of preparing and viewing cells under the electron microscope.

            (b)    Draw a fully labelled diagram of a generalized animal cell as seen under the electron microscope

            (c)     Give five differences between this cell and a chlorenchyma cell.

            (d)    Why are electron microscopes not found in labouratories in Cameroon schools?

            (5, 8,5,2 mks)

            A:

            (a) Disadvantages of preparing and viewing cells under the electron microscope

            -Preparation of material is time consuming

            -Requires staining with heavy metals which may produce artefacts

            -Fixation of material for viewing is done in a vacuum and cells cannot be observed alive.

            -Produces black and white images seen in one plane

            -Cannot be used without electricity

            (b)

            Animal cell under an electron microscope

            (c)      Dfferences between animal cell and chlorenchyma

            Animal cell

            Chlorenchyma

            No cell wall 

            Cell wall made of cellulose

            No chloroplasts and chlorophyll

            Has chlorophyll found in the chloroplast

            There is microvilli and centrioles present

            Absent

            Tacks pyrenoids              

            Has granules and pyrenoids for starch Storage

            Small peripheral vacuoles

            Large central vacuoles

             

            (d)      Why electron microscopes are not found in labouratories in Cameroon schools

            -       They are very expensive to buy and are very bulky

            -       Requires expert training to manipulate

            They are complicated and difficult to repair

            Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

              Q:

              (a) Cell membranes are fluid and porous in nature. Discuss why this is important in relation to the functions of the following organelles

              (i)    cell membrane (ii) rough endoplasmic reticulum (iii) Golgi apparatus

              (b) Describe the functions of lipids and proteins within the plasma membrane.

              (4, 3, 3,10 mks)

              A:

              (a) (i) Importance of fluidity of plasma membrane

              -The plasma membrane must be porous and fluid to function as a selective barrier that helps to regulate the chemical composition and pH of the cell. They thus enable some substances to readily pass through while impeding the entrance or exit of others.

              -It allows the membrane to enable sufficient traffic of oxygen, nutrients and waste products. It also makes the membrane to flex, stretch, self-repair, grow, bud vesicles, interact with cytoplasmic structures and be capable of division.

              -It also allows the membrane to orientate cell junctions for communication between cells.

              (i)      Rough endoplasmic reticulum

              -Fluidity is essential to provide a large surface area inside the cell for enzymatic activities, and to divide the cell into compartments for different biochemical functions.

              -Ribosomes easily attach on the surfaces. These are the sites of protein synthesis.

              -lipids are also synthesized in this organelle, and used to build cellular membranes.

              -Fluidity allows them to bud vesicles which contain assembled proteins and lipids.

              -The fluid nature allows the transport of various chemical substances from one part of the cell to another, including regulating cytoplasmic calcium.

              (ii)      Golgi apparatus 

              -Fluidity is the key feature of the Golgi apparatus, which functions mainly in processing and packaging protein compounds made in the rough endoplasmic reticulum.

              -The organelle is well developed in secretory cells where vesicles containing substances for secretion pass to the Golgi apparatus to form new Golgi apparatus membranes, which bud secretory vesicles. The vesicles move' to the plasma membrane or another membrane within the cell, depending on its destination.

              (b) Functions of lipids in the plasma membrane

              -Lipids confer fluidity to the cell membrane and make up some 70% of its composition.

              -There are three types of lipids in the membrane; phospholipids, cholesterole and glycolipids. They all have polar head groups and non-polar tail groups, and assembles tail to head, giving the bi-layer structure, characteristic of all membranes. Membranes are held together by hydrophobic interactions between lipids. Lipids diffuse in the plane of the membrane, and prevent solidification by adjusting viscosity. This is important for enzyme activation and vesicle formation. Cholesterol enhances fluidity.

              -Lipids are involved in the passive transport of substances across membranes.

              -Hydrophobic molecules such as oxygen and hydrocarbons can dissolve and pass through the lipids of the membrane easily.

              -Lipids are impermeable to all ions.

              Functions of proteins in the plasma membrane

              -There are two types of membrane proteins; integral and peripheral proteins.

              -Integral proteins span the membrane while peripheral proteins are attached to the surface of the membrane, and are involved in anchoring the membrane to the sub-membrane cytoplasmic structures. A single intergral protein may perform a combination of tasks such as; active transport of substances to regulate pH and ion concentration, enzyme functions, receptor sites for hormones and cell adhesion forming intercellular junctions.

              Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                Q:

                (a) Explain the advantages eukaryotic cells derive from being copartmentized by many internal membranes.

                (b)  Increased physical exercise leads to increase in size of muscles. Explain how this would affect the size, number or activities of organelles in a muscle cell.

                (c)    (i) Descibe how cancer cells differ from normal body cells.

                (11)  How does chemotherapy slow the growth of cancerous cells? State the side effects.

                (3,7,6,4 mks)

                A:

                (a)    Advantages of internal membranes of eukaryotes

                -Membranes separate metabolic processes and allow processes that require different conditions fo be carried out simultaneously.

                -They also increase the total surface area of membranes, where many metabolic processes occur.

                (b)    Effect of increased muscle activities on organelles in the muscle fibre

                -As a muscle cell grows, ribosomes, endoplasmic reticulum and Golgy bodies would work together to produce more protein and cell membrane.

                -Microfilaments made of the protein actin would increase in number since they are responsible for the contractile activity of muscles.

                -Smooth ER that stores calcium involved in the contraction process would increase in she and grow.

                -Mitochondria that provide energy for the contraction of muscles and other cellular activities would increase in number

                (c)    (i) How cancer cells diffed from body cells

                -Cancer cells escape from the control mechanisms that regulate division in normal cells

                -They do not need to be anchored to a solid surface to grow.

                -They seem to be unaffected by density­dependent inhibition and will pile up on one another in cell cultures.

                -They either donot require growth factors or manufacture their own growth factors.

                -Unlike normal cells, cancer cells can divide indefinitely. If they stop dividing they stop at random points in the cell cycle, not at the restriction points.

                (ii)  How chemotherapy slows the growth of cancerous cells and side effects

                -Cancer is uncontrolled cell division. Chemotherapy and other cancer therapies like radiation slow tumour growth by interfering with cell division.

                -Cell division is most rapid in the skin and digestive tract lining, where it replaces lost cells, so the side effects of chemotherapy are greatest on the skin and intestinal lining.

                -The side effects of chemotherapy are hair loss, nausea, and loss of appetite.

                Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                  Q:

                  Briefly describe the relationship between the structures and functions of the main tissues in animals      (5x4 mks)

                  A:

                  Animal Tissues and adaptations to functions

                  -Tissues are groups of cells with a common structure and function. There are four types of tissues in animals: epithelial tissue, connective tissue/supp orting tissue, (including blood), muscle tissue and nervous tissue, all having different structures that are especially suited to their functions.

                  (a)    Epithelial tissues

                  -They cover' the outside of the body and lines organs and cavities. Their cells are arranged in sheets.

                  -The cells of an epithelium are closely joined with little material between them

                  -The tight packing enables the epithelial to function as a barrier protecting against mechanical injury, invasive microbes and fluid loss

                  -Free surface of the epithelium is exposed to air or fluid, whereas the cells at the base are attached to a basement membrane, a dense mat of extracellular matrix.

                  -Epithelia are classified according to the shape of the cells (squamous, cuboidal, or columnar and ciliated) and the number of layers (simple, stratified, or pseudostratified).

                  -Depending on the epithelium type and its location it may serve protective, absorptive, or secretory functions.

                  -Epithelia cover all internal and external body surfaces.

                  -A special type of epithelium, endothelium, makes up the walls of blood and lymph vessels.

                  (b)     Connective/Supporting Tissue

                  -Connective tissues consist of cells and extracellular matrix. They may serve different functions: structural support (e.g. bones), connections (e.g. ligaments and tendons), protection (e.g. fat pads), transport of respiratory gases and defence (blood).

                  -Connective tissue is made of cells, (e.g. fibroblasts, chondrocytes and osteocytes); extracellular fibres (e.g. reticular, elastic and collagen); and ground substance.

                  -Cells: provide defence and produce the supportive structures, fibroblast (secrete the protein ingredients of the extracellular matrix e.g. collagen and elastin), macrophages (amoeboid cells that engulf bacteria and dead cell debris by phagocytosis), mast cells (contain small granules to prevent blood clotting, increase permeability of capillaries and venules)

                  -Materials: e.g. hyaluronic acid, chondroitin sulphate, heparin sulphate function as a medium through which nutrients can diffuse from blood vessels to nourish the cells *

                  -Structural glycoproteins: e.g. fibrin, collagen, elastic fibres are proteins that give connective tissue its strength

                  -long threads made of elastin protein join connective tissue to adjacent tissue

                  -Depending on the type (e.g. loose, dense), connective tissue may serve different functions; including structural support, connections, elasticity and protection.

                  -Dense connective tissue or fibrous connective tissue: contains a great proportion of fibres, fewer cells and less ground substance. E.g tendons (attach muscles to bones), ligaments (join bones together at joints) -Loose connective tissue has an abundance of cells and ground substance, but relatively few fibres. It is soft and pliable and

                  serves as a kind of packing material between other tissues and organs.

                  -It is found between muscles, allowing one to move freely over the other.

                  -It supports small blood vessels, lymphatic vessels and nerves.

                  -Adipose tissue is made of loose connective tissues with a high population of adipocytes

                  -Cartilage is a form of connective tissue that is much firmer than dense connective tissue.

                  It consists of a dense network of fibres embedded in a gel-like intercellular material which confers firmness but also permits flexibility. The cells are called chondrocytes (produce collagen and chondroitin sulphate)

                  -There are various types of cartilage: hyaline (found at the end of bones where they articulate with one another and found in the nose, larynx, trachea and bronchi of the respiratory system and the precursor of the vertebrate skeleton), elastic (very flexible and when deformed, it immediately returns to normal position, and is found in the external ear, epiglottis and auditory tube)’ and fibrocartilage (found in intervertebral disks and associated with dense fibrous tissue in tendons and ligaments

                  -Bone is a mineralized connective tissue made of hydroxyapatite and osteoblasts.

                  -Compact bone consists of repeating unit called osteon or Haversian system

                  -Bone is a rigid firm form of connective. The hardness of a bone is caused by the presence of calcium phosphate; the small degree of elasticity possessed by bone is caused by the presence of organic collagen fibres. The cells of bone are called osteocytes.

                  Bone are of two types; compact and spongy bone

                  (c)    Muscle tissue

                  -Muscle cells are contractile cells. Specialized proteins allow the cells to 'shorten. Their ability to contract provides a mechanism for movement of the internal organs and locomotion of the entire organism.

                  -Muscle tissue can be divided into 3 major types: Skeletal, Cardiac and Smooth.

                  -Skeletal muscle is attached to bones.

                  -Cardiac muscle is found in the heart.

                  -Smooth muscle is found in vessels,'ducts, skin, and internal organs.

                  -Muscle tissue may be controlled by nerves, hormones, local chemicals, or itself depending on the type and location.

                  -Skeletal muscles are under voluntary control. They are attached to bones or fascia and constitute the flesh of the limbs and body wall. They contain fibres (myofibrils), are long, multinucleated and arranged in parallel bundles, -unlike smooth and cardiac muscle, each skeletal myofibril is innervated by a neuron.

                  -By light microscopy, the cells of both cardiac and skeletal muscle show the presence of transverse striations.

                  -For this reason, both of these muscle types are referred to as "striated"

                  -The striated appearance results from the presence of a highly organized network of actin and myosin protein filaments which utilize cellular energy and function in muscle contraction.

                  -Smooth muscle is not under voluntary control and comprises the walls of most of the viscera and blood vessels of the body. There is one centrally placed nucleus per cell.

                  -Cardiac muscle is involuntary, striated in appearance and contracts rhythmically and automatically. It is found only in the myocardium (the muscle layer of the heart).

                  -Each cell has a single, centrally located nucleus and joins end to end with other cardiac muscle cells at specialized junction zones called intercalated discs. These junctions allow the spread of excitation to pass from one fibre to another and harness the contraction of individual cells so that overall muscle shortening can occur.

                  (d)    Nervous Tissue

                  -It is composed of two major types of cells: neurons and support cells (glia).

                  -Neurons have specialized dendrites for receiving signals, a cell body for cell maintenance and integration, an axon for sending signals rapidly over long distances, and many terminals to make synapses with other cells.

                  -The cell bodies of neurons in the peripheral nervous system (PNS) are located in groups called ganglia.

                  -Glial (glue) cells are supportive cel is, providing nourishment and other aids to neuron function.

                  -Nerves are bundles of axons surrou ided by glial (Schwann) cells and some connective tissue.

                  Individual axons may be either sensory or„ motor in function.

                  -astrocytes (astroglia) provide physical support to neurons clear up debris surround capillaries in the brain (blood brain barrier)

                  -Oligodendrocyte produces myelin sheaths around the axon in the central nervous system (CNS)

                  -Schwann cells produce myelin sheaths around axon in the peripheral nervous system

                  -The cell body contains the nucleus and metabolic machinery of the cell. Proteins and neurotransmitter substances that carry signals between cells are synthesized there.

                  -The neuroglia cell nuclei serve several important functions: Provide nutritional support for the neurons, surround blood vessels to regulate what types of substances are allowed to pass to the neurons. This function is referred to as the blood brain barrier, form myelin sheaths around axons to speed impulse transmission and engulf “foreign invaders such as bacteria.

                  Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                    Q:

                    17.      (a) (i) Describe the chemical content of the plasma membrane.

                    (11)  Differentate between smooth and rough endoplasmic reticulum.

                    (b)    What are the morphological, chemical and functional similarities and differences between lysosomes and peroxisomes?

                    (c)    What are the components and functions of the cytoskeleton?    (5,4,5, 6 mks)

                    A:

                    (a)    (i) Chemical constituents of plasma membrane

                    -The main constituents of the plasma membrane are phospholipids, proteins and carbohydrates.

                    -The phospholipids which are amphipathic molecules are regularly organized in the membrane according to their polarity: two layers of phospholipids form the lipid bilayer with the polar part of the phospholipids pointing to the exterior of the layer and the non-polar

                    phospholipid chains in the interior. -Proteins can be found embedded in the lipid bilayer and there are also some carbohydrates bound to proteins and to phospholipids in the outer face of the membrane.

                    -Molecules of cholesterol are present which prevents membrane solidification.

                    (ii) Differences between smooth and rough endoplasmic reticulum

                    -The endoplasmic reticulum is a delicate membranous structure contiguous to the nuclear membrane and present in the cytoplasm. It forms an extensive net of channels throughout the cell and is classified into rough or smooth types.

                    -The rough endoplasmic reticulum has a great number of ribosomes attached to the external side of its membrane while smooth endoplasmic reticulum does not have ribosomes attached to its membrane.

                    -The main functions of the rough endoplasmic reticulum are synthesis and storage of proteins made in the ribosomes while the smooth endoplasmic reticulum plays a role in the synthesis of lipids, and in muscle cells, it is important in the conduction of the contraction stimulus.

                    (b)    Morphological, chemical and functional comparism of lysosomes and peroxisomes Similarities:

                    Lysosomes and peroxisomes are small membranous vesicles that contain enzymes and enclose residual substances from internal or external origin degrading them.

                    -They are both enclosed by a single unit membrane

                    Differences:

                    -Lysosomes have digestive enzymes (hydrolases) that break substances to be digested into small molecules while peroxisomes contain enzymes that degrade mainly long-chained fatty acids and amino acids and that inactivate toxic agents including ethanol. They contain the enzyme catalase, responsible for the break down of toxic hydrogen peroxide (H2O2) to water and molecular oxygen.

                    (c)    Components and functions of the cytoskeleton

                    -The cytoskeleton is a network of very small tubules and filaments distributed throughout the cytoplasm of eukaryotic cells. It is made of microtubules, microfilaments and intermediate filaments.

                    -Microtubules are formed by molecules of a protein called tubulin. Microfilaments are made of actin and myosin, the proteins that participate in the contraction of muscle cells.

                    -The cytoskeleton is responsible for the support of the normal shape of the cell; it also acts as a facilitator for substance transport across the cell and for the movement of cellular organelles. For example, the sliding between actin-containing filaments and the protein myosin “creates pseudopods.

                    -In cells of the phagocytic defense system, like macrophages, cytoskeleton is responsible for the plasma membrane projections that engulf the external material to be interiorized and attacked by the cell

                    Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                      Q:

                      17.     (a) Why are tissues fixed, sectioned and stained befôre being viewed under a microscope?

                      (b)     Describe the structures and functions of Lysosomes

                      (c)      Outline the main stages of cell fractionation.

                      (6, 8, 6 mks)

                      A:

                      (a)      Tissues are fixed to maintain them in life like forms. The tissues are killed and the proteins positioned before degenerative changes occur.

                      -They are sectioned to be of thin slices that would allow light to pass through them to enable viewing.

                      -Tissues are stained to render them visible by increasing the contrast between the various structures.

                      -Stains react chemically with the structures of the cell or adhere to them.

                      (b)     (i) Structure and functions of lysosomes

                       -Lysosomes are simple sacs containing digestive enzymes such as proteases, nucleases and lipases.

                      -They are surrounded by a single unit membrane and found only in eukaryotic cells.

                      -These enzymes are synthesized on the rough endoplasmic reticulum arid carried to the Golgi apparatus.

                      -The Golgi vesicle containing the enzymes buds off forming primary lysosomes.

                      -Larger secondary lysosomes are formed by the fusion of primary lysosomes with small vacuoles -They also fuse with worn out organelles (autophagosomes) and eliminate them.

                      Functions

                      -Digests particles made in the cell or taken into the cell from the outside through endocytosis.

                      -They carry out autophagy; fuse with unwanted particles and digest their content, which are used as food.

                      -The contents are sent out through exocytosis if they were bacteria engulfed through phagocytosis.

                      -They help in the breakdown and elimination of ageing organelles in cells.

                      -They release enzymes out of cells that help in the replacement of cartilage with bone. Acrosomes release enzymes that digest the egg membrane for sperm penetration

                      -Are implicated in the reabsorption of the tadpole tail during metamorphosis and digestion of the increased uterus after birth.

                      (c)       Main stages of cell fractionation

                      -Cell fractionation involves the separation of cell organelles to study their structures

                      -Life tissue is chopped in cold isotonic-buffer solutions or ruptured by ultrasonic waves.

                      -Chopped tissue is ground in a homogeniser

                      -The homogenate is transferred to a centrifuge which spins the mixture at different speeds -Organelles sediment separately

                      (ultracentrifugation)

                      Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                        Q:

                           (a) Explain the main importance of the following organelles to plant cells.

                        (i)    cell wall (ii) vacuole

                        (b) (i) Draw a well abelled diagram of a sensory neurone.

                        (ii)    State the various neuroglia cells of the central nervous system and outline their specific functions.           (12,4,4 mks)

                        A:

                        (a) (i) Importance of cell wall to plant cells

                        -The matrix of cell wall consists of polysaccharides divided into pectins and hemicellulose.

                        -The deposit may be cellulose in some cells or covered with lignin.

                        -Provides mechanical strength and skeletal support to cells and entire plant.

                        -Resists expansion, allows development of turgidity when water enters cells by osmosis. Supports cells and organs that lack secondary growth e.g. leaves

                        -Prevents cells from bursting when in a dilute solution

                        -Orientation of cellulose micro fibrils helps to limit and control cell growth and shape.

                        -     Forms the major pathway for water transport i.e. apoplast by the system of interconnection of the cell wall held by middle lamellae.

                        -     Cell walls have minute pores through which plasmodesmata passes, forming livirg connections between cells and allowing linking of all the protoplast in a system called the symplast.

                        -     Cell walls develop a coating of waxy cutin, the cuticle, which reduces water loss and prevents infection on external cell surfaces.

                        -     The walls of the xylem and sieve tubes contain lignin and are adapted for long distance transportation of water.

                        -Cell walls of endodermal cells of roots contain suberine that forms a barrier to water movement.

                        -Some cell walls are modified to store food such as hemicelluloses stored in some seeds.

                        -Cell walls of cells that transfer substances provide large surface area for efficiency.

                        (ii)   Importance of vacuoles to plant cells

                        -The vacuole is a fluid filled sac surrounded by a single unit membrane called tonoplast.

                        -Passage of water into concentrated cells occurs through the partially permeable tonoplast.

                        -This osmotic intake of water is important for expansion during cell growth.

                        -Contains pigments (anthocyanins) which are coloured and responsible for colour of flowers, fruits, buds and leaves.

                        -This attracts insects, and birds for pollination.

                        -May contain hydrolytic enzymes and act as lysosomes.

                        -Waste products may accumulate in vacuoles e.g. tannins and alkaloids and prevent consumption of those parts by herbivores.

                        -Some dissolved substances in vacuoles act as food reserves, which are utilised when needed e.g. sucrose and mineral salts.

                        (b) (i)

                        sense cell or

                        Diagram of a sensory neurone

                         

                        (b) (ii) Neuroglia cells are the parking and supporting tissues of the nervous system. The cells and their functions are;

                        -Protoplasmic astrocyte: Stores energy as glycogen

                        -Fibrous astrocyte: Provide nutrients from blood to neurones

                        -Microglia: Contains lysosome and is phagocytic

                        -Oligodendrocyte: Produce insulating myelin surrounding the axon

                        -Schwann cell: Produce insulating myelin

                        -Ependymal cell: Lines the brain and spinal cord.

                        Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                          Q:

                          Give an illustrated account of the structure and functions of the following cell organelles.

                          (a) Rough endoplasmic reticulum (b) Cilia

                          (c) Golgi apparatus (d) ribosomes. (5x4 mks)

                          A:

                          (a) Rough Endoplasmic Reticulum

                          -They are made up of a network of sac like tubular cavities called cisternae, bounded by a unit membrane. The membranes are covered with ribosomes and are continuous with the nuclear membrane. They are prominent in enzyme secreting cells.

                          Diagram of the endoplasmic reticulum

                          Functions:

                          -Provide large surface area for synthesis

                          -Permit rapid transport of synthesised molecules (proteins) within cells and, from inside to outside cells.

                          (b)    Cilia

                          -They develop from basal bodies produced when the centrioles of some cells divide. They are made up of longitudinal fibrils, two in the centre surrounded by nine outer pairs; all enclosed in a unit membrane. Make a large diagram of the fibrils.

                          cell membrane

                          Structure of cilia

                          Functions:                                 

                          -Kicks off liquids and particles away from surfaces by rhythmic contraction and relaxation,

                          -Used in locomotion by some cells.

                          (c)    Golgi apparatus 

                          -They appear as closely packed parallel curved pockets in cross section. The pockets are bounded by unit membranes and are called cisternae.

                          -Tiny vesicles arise from the edges of the cisternae. Some of these vesicles become lysosomes while some fuse with and enlarge the plasma membrane. Others carry secretions to the plasma membrane for release to the exterior.

                          -Carbohdrates are added to proteins from the ER in the Golgi body to foxm glycoproteins (mucus)

                          Diagram of the Golgi apparatus

                          (d)    Ribosomes

                          They are small near circular structures made up of two sub units. In prokaryotic cells; the ribosome is 70s while those of eukaryotic cells are 80s.

                          Functions:

                          -Sites of protein synthesis. Moves along mRNA molecule, one or many (polysomes). When at a particular codon, tRNA with the corresponding anticodon brings coded amino acid for protein synthesis.

                          Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                            Q:

                            (a) How has our ideas on the structure of plasma membranes been influenced by the electron microscope?

                            (b)    Make a well labelled diagram of a plant cell as seen under the electron microscope.

                            (c)    (i) Given that the membrane of this cell is 7nm thick, calculate the magnification of a membrane drawn 6cm thick.

                            (ii)  What is the difference between magnification power and resolution power of a microscope?      (6, 7,7 mks)

                            A:

                            (a)    Influence of Electron microscope on our idea of membrane structure.

                            -The electron microscope offers a higher resolution and magnification power.

                            -This has enabled the detailed structure of the

                            plasma membrane to be observed and studied.

                            -The various component molecules are distinctively seen to compose of proteins, phospholipid bilayer and molecules of cholesterol.

                            -It has also revealed that the phospholipids have phosphate heads facing outwards and hydrocarbon tails facing inwards.

                            -Some proteins go through the membrane while others do not.

                            (b)

                             Ultrastructure of a plant cell

                            (i) -Drawn thickness = 6cm i.e. 6 x 102 = 0.06m

                            .'.Drawn thickness =(6 x IO-2) m

                             thickness » 7nm » (7 x 10-9) m

                            Drawn thickness = actual thickness x magnification

                            Magnification =drwan thickness / actual thickness

                            Substitute:

                            Magnificaton = 0.06/7*10-9 

                            Mag =  8.57 *106

                            NB: Measure the thickness of the diagram drawn using your ruler if it is not given arid use the value obtained as the drawn thickness when necessary.

                            (ii)  Differences between magnification and resolution

                            -Magnification gives a larger image for clear viewing without distinguishing between components while the resolution shows distinct parts of the object viewed showing the various components as distinct entities.

                            Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                              Q:

                              (a) Describe the role of

                              (i) carbohydrates (ii) proteins and (iii) lipids in the structure of plant and animal cells.

                              (b) How do antibiotics treat some bacterial diseases?          (16,4 mks)

                              A:

                              (a)    (i) Role of carbohydrates in the structure of plant and animal cells.

                              -The micro fibrils of plant cell wall contains cellulose molecules held by hydrogen bonds which makes it rigid and protect the internal structures from mechanical injury.

                              -Plant cells store reserved food as starch

                              -Glucose when in some cells alter the osmotic concentration which may lead to the influx of water enabling such cells attain turgidity.

                              -Carbohydrates combine with protein at cell membranes to form glycoproteins which are antigens.

                              -They help to distinguish between self and non­self.

                              (ii) Proteins

                              -Channel and carrier proteins at cell membranes help in the transport of substances across membranes.

                              -Some of the proteins go through the membrane and form pores where simple diffusion occurs while others float and transport substances by rapidly spinning.

                              -Some proteins in cell membranes are enzymes. They catalyse metabolic reactions at cell surfaces.

                              -The structure of some proteins at cell membranes gives a particular shape which acts as reception sites for some hormones.

                              -Plasma proteins like fibrinogen help to form a clot, thereby preventing excessive loss of blood when vessels are wounded.

                              -Some cells contain collagen and keratin which gives mechanical strength.

                              (ii) Lipids

                              -Cell membranes contain a phospholipid bilayer that controls the movement of polar molecules within cells.

                              -The layer is fluid with the phosphate heads facing outwards and hydrocarbon tails inward. This gives stability to the membrane.

                              -Some cells contain a waxy outer covering which prevents desiccation.

                              -Cholesterol present at cell membranes prevents close parking of phospholipids, thereby softening cell membranes, making them flexible.

                              -Cholesterol plugs also prevent the escape of polar molecules.

                              (b)    How antibiotics treat bacterial diseases

                              -Destroy pathogenic bacteria by digesting them (biostatic)

                              -Inhibit growth of the pathogenic bacteria

                              -Interfere in the metabolism of the pathogen and block protein synthesis, nucleic acid synthesis and disrupt the functioning of the cell membrane, capsing the pathogen to die.

                              Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                                Q:

                                12.     (a) Briefly explain the mechanism of the following processes giving examples of where they occur.

                                (1)   Diffusion (ii) Active transport

                                (ii)      Pinocytosis (iv) Phagocytosis

                                (b) (i) List the features that affect the rate of diffusion (ii) Suggest why active transport is affected by oxygen concentration and diffusion is not.                      (4,4, 4,2, 3, 3, mks)

                                A:

                                (a)    (i) Diffusion

                                It is the net movement of molecules or ions from a region of high concentration to that of low concentration.

                                It occurs in living and non-living systems where ever there is a concentration gradient and does not require energy e.g. movement of CO2 and O2 across respiratory surfaces such as gills of fish and alveoli in mammals.

                                (iii)  Active transport

                                -It is the movement of substances against a concentration gradient by the use of energy from ATP across cells.

                                -Cells that carry out active transports regularly have numerous mitochondria and high concentrations of ATP.

                                -Actively transported molecules can be carried by protons or protein molecules e.g. sodium/potassium pump which pumps Na+ out of the cell and K+ in, to generate impulses; active absorption of digested food in the gut and active absorption of mineral ions by root hairs.

                                (iv)     Pinocytosis

                                -Form of endocytosis by which a living cell engulfs minute droplets of liquid by the use of energy.

                                - Involves the infolding or invagination of the cell surface membrane forming vesicles e.g. uptake of nutrients from the follicles by human egg cells, pick up of thyroxin from the follicles of the gland.

                                (v)       Phagocytosis

                                -Process by which solid substance, are brought inside the cell by invagination of cell membranes using energy.

                                -The cell invaginates to form a depression containing the particles.

                                - The depression pinches off to form a vacuole, the inner surface derived from the outer surface of the cell membrane e.g. mode'of feeding of amoeba, action of phagocytes to destroy foreign particles.

                                (b)    (i) Features that affect the rate of diffusion

                                -Cell surface area, concentration gradient, type of molecule, length of diffusion path, temperature and Permeability of path

                                (ii)  Why active transport is affected by O2 concentration while diffusion is not affected.

                                -Active transport uses energy derived from ATP.

                                -     ATP is produced during aerobic respiration.

                                -     A decrease in O2 concentration will reduce the amount of ATP generated which will affect active transport.

                                -     Diffusion is a passive process which does not require energy in the form of ATP.

                                Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                                  Q:

                                  (a) (i) What are the characteristics of meristematic cells?

                                  (ii)   Comment on the distribution and functions of the various specialised forms of parenchyma.

                                  (b) Compare the structure of collenchyma and sclerenchyma tissues.            (5,10,5 mks)

                                  A:

                                  (a) (i) Characteristics of meristematic cells

                                  -Meristematic cells are small and thin walled.

                                  -The cytoplasm is dense and the nucleus occupies a large part of the cell.

                                  -They are active and capable of further cell division

                                  (ii)    Distribution and functions of specialised forms of parenchyma

                                  -Epidermis:

                                  Thes are continuous layers of cells at the surface of plants. Contain guard cells at intervals which function in gaseous exchange and transpiration. Epidermal cells of leaves and stems have waxy suberine called casparian strip that regulates movement of water and» mineral salts across the root.

                                  -Pericycle:

                                  Found in roots between the endodermis and central vascular tissue. Divides to form lateral roots and contributes to secondary growth.

                                  (b) Comparism of'collenchyma and sclerenchyma

                                  Collenchyma

                                  Sclerenchyma

                                  Has additional cell wall deposits of cellulose, pectin, hemicellulose

                                  Additional cell wall deposit is lignin

                                  No intercellular air spaces

                                  No intercellular air spaces

                                  Mature cells are living

                                  Mature cells are dead

                                  No pits

                                  Contain simple pits

                                  One type

                                  2 types, fibres and sclereids

                                   

                                  Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                                    Q:

                                    (a) What is a unit membrane?

                                    (b)     Give the functions of the cell membrane

                                    (c)     Write an account of the cell cycle, involving a mitotic nuclear division, highlighting the events occurring in each phase. (4,6,10 mks)

                                    A:

                                    (a)    Definition of a unit membrane

                                    -A unit membrane is the external boundary of cells and some organelles.

                                    -All membranes have the same structure as revealed by electron micrograph.

                                    -A unit membrane is trilamella with a phospholipid bilayer and protein molecules.

                                    -The phospholipids are fluid with phosphate head that faces outwards and hydrocarbon tails facing inwards.

                                    -Some proteins go through the membrane while others do not.

                                    -The membrane is 7nm thick.

                                    (b)     Functions of cell membranes

                                    -Controls passage of materials in and out of cells by the use of channel and carrier proteins.

                                    -Recognition of other cells by glycoproteins called antigens

                                    -Reception site for hormones and neurotransmitters.

                                    -Transmission of nerve impulses

                                    -Insulation of nerves

                                    -Forms barrier between cells and their surrounding membranes inside cells (intracellular membranes) act as reaction surfaces, act as intracellular transport system and provide separate compartments isolating different chemical reactions

                                    (c)     The sequence of events between one cell division and the next

                                    -     This sequence is called the cell cycle.

                                    At interphase, new materials/organelles are synthesised. G1 phase - growth occurs^ DMA replicates. S phase - each chromosome becomes 2 chromatids. G2 phase - mitochondria/chloroplast divide. The M phase has 4 stages.

                                    Prophase:

                                    Chromosomes shorten and thicken, centrioles move to opposite poles (in animal cells), nucleoli disappear, nuclear membrane disappears, spindle forms.

                                    Metaphase:

                                    Chromosomes line up around equator centromeres attached to spindle fibres.

                                    Anaphase:

                                    Centromeres split, separated chromatids pulled towards poles.

                                    Telophase:   

                                    Chromatids reach poles, chromatin reformed, spindle disintegrates, centrioles replicate, nuclear membrane reforms, nucleoli visible.

                                    C phase:

                                    Cell divides (cytokinesis) to become two daughter cells with same chromosome number as parent cell, equal distribution of organelles, cell plate forms in plant cells.

                                    -     G1 phase of interphase / cycle continues.

                                    -      The length of the cell cycle depends on the type of cell, temperature and other physiological factors 'e.g. onion root tips may divide every 20 hours.

                                     

                                    Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                                      Q:

                                      (a) Epithelial tissues have different modifications in different parts of the body. Discuss the importance of the modifications in their various locations.

                                      (b)    Distinguish between striated and unstraited muscles

                                      (c)    Why are cardiac muscles described as myogenic?          (13, 5,2 mks)

                                      A:

                                      (a)    Squamous epithelium of the blood vessels, alveoli of lungs and kidney is flat, thin and smooth. This facilitates diffusion and lubricates surfaces for movement

                                      -Cuboidal epithelium of the salivary, pancreatic, thyroid glands and lining of many ducts have cube shaped hexagonal cells. They carry out secretary functions.

                                      -Columnar epithelium of the stomach and intestines are tall cells associated to mucus secreting goblet cells. They have microvilli at their free surface end. In the stomach they secrete mucus that prevents auto digestion. In the intestine, the microvilli increase the surface area for absorption.

                                      -Ciliated epithelia contain cilia at their free surface end and are associated with mucus secreting goblet cells. In the oviduct they help to push the zygote to the womb, distribute cerebrospinal fluid in the ventricles of the brain and clear away dust and bacteria in the respiratory tract.

                                      -Stratified epithelia of the external skin are several layers thick. The outer layers are dead cells and are cornified. This offers protection. In the vagina and buccal cavity they prevent abrasion.

                                      cilia at free surface end

                                      Squamous epithelium Ciliated epithelium

                                      (b) Differences between striated and unstraited muscles

                                      Striated (voluntary, skeletal) muscle

                                      Unstriated (smooth, involuntary) muscle

                                      Elongated and thick

                                      Spindle shaped and thin

                                      Multinucleated

                                      Uninucleated

                                      Cuboidal epithelium

                                      Columnar epithelium

                                      Occur attached to the skeleton directly to bones or by tendons

                                      Occur in sheaths in the walls of some organs e.g. iris

                                      Has cross striations

                                      No cross striations

                                      Under the control of the voluntary nervous system

                                      Under the control of the automatic nervous system

                                      Contracts quickly and powerfully and fatigues relatively quickly

                                      Contracts slowly and fatigue slowly

                                       

                                      (c)    Why cardiac muscles are myogenic

                                      -The impulses that cause their contractions originate from the heart muscle itself. They contract rhythmically from the time of formation till the death of the organism.

                                      Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

                                        Q:

                                         (a) Make a well labelled diagram of the ultra­structure of a plant cell.

                                        (b)    In a tabular form, give the differences between the cell drawn and an animal cell.

                                        (c)    Describe the ways by which substances move in and out of living cells.                (7,5, 8 mks)

                                        A:

                                         

                                         

                                         

                                        (b) Differences between plant and animal cells

                                        Plant cell

                                        Animal cell

                                        Outer covering is cellulose cell wall giving it a rigid shape

                                        Outer covering is cell membrane, no rigid shape

                                        Contains chloroplast with chlorophyll

                                        Absent

                                         

                                        Large central vacuole with peripheral nucleus

                                        . Small peripheral vacuoles and large central nucleus

                                        Small cytoplasm

                                        Larger cytoplasm

                                        No centriole and lysosomes

                                        Centrioles and lysosomes present

                                        Plasmodesmata present

                                        Absent

                                        Store food as starch

                                        Food reserved as glycogen

                                         

                                        (c) How substances move in and out of cells

                                        -Simple diffusion: Movement of substances across cells through pores following a concentration gradient e.g. CO? and O2 through channel proteins. -Facilitated diffusion: Movement of glucose and amino acids by the help of carrier proteins. The proteins pick up the substances and rapidly spin, dropping them inside the cells.

                                        -Active transport: Carrier proteins use energy to transport substances against their concentration gradients e.g. uptake of glucose at the intestine, sodium-potassium pump during the transmission of impulses, and active loading of sugar to the phloem. Active bulk uptake of liquids (pinocytosis) or solids (phagocytosis) and bulk transport of substances out of cells using energy (exocytosis).

                                        -Osmosis: Movement of water from an area of high water potential to those of low water potential through a selectively permeable membrane e.g. water uptake by root hairs, gain of turgidity by cells.

                                        Year: June 2018 | Subject: Biology | Topic: CYTOLOGY & HISTOLOGY

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